Approximately 15% of reproductive dysfunctions are caused by an absence of ovulation (anovulation). Sometimes anovulation presents with irregular menstruation, increased hair growth, etc. The majority of anovulatory patients usually have polycystic ovaries.
Ovulation can be induced using drugs (clomiphene citrate, metformin, Femara) which reset hormonal irregularities. 50% of anovulatory patients achieve normal cycles with these therapies. Once the follicle reaches maturity (more than 18 mm in diameter), ovulation is triggered with hCG and couples can engage in scheduled coitus or AI. Women without a male partner can have artificial insemination by donor (AID).