Our Team

Our medical team, specialised in fertility, is made up of professionals with extensive experience in assisted reproduction and a shared vocation: to support you throughout the entire process and help you fulfil your desire to become a mother. Each fertility specialist doctor and every professional at our centre works with dedication, empathy and medical precision. Thanks to more than three decades of experience, we have helped thousands of people discover where babies come from: science, trust and the care with which we treat every case

Our fertility specialist doctors and clinical embryologists have continuous training and a well-established track record in all areas of fertility. This allows us to offer personalised, up-to-date treatments with real results, supported by scientific evidence and by the testimony of those who have trusted us since 1992. The dedication and sensitivity of our team have made FIVMadrid one of the clinics with the most recognised fertility specialists in Madrid

A multidisciplinary team to support you at every stage

Since 1992, at FIVMadrid, we believe that the best results are achieved when medical knowledge is combined with a human and close approach

Our team is made up of gynaecologists, embryologists, laboratory staff and a Patient Care department specialised in infertility that supports you step by step, resolving your doubts before, during and after treatment

We believe in a human, transparent and professional approach, where trust and constant communication are just as important as medical technology. Because since 1992 we have worked to ensure that every patient feels heard, understood and confident

Dr. Eleuterio R. Hernández de Miguel

FOUNDER OF FIVMADRID | Doctor of Medicine and Surgery
1976 | rotating internship
Hospital Clínico de Zamora. Zamora. Spain
1977–79 | RESIDENCY
Resident in Obstetrics and Gynaecology. “Virgen de la Vega” Hospital. Salamanca. Spain
1979 | ADDITIONAL TRAINING
Human Contraception Course. Johns Hopkins University. Baltimore, Maryland. USA
1980 | ADDITIONAL TRAINING
Guest Worker. Pregnancy Research Branch. NICHD, National Institute of Health. Bethesda, Maryland, USA.
1981 | ADDITIONAL TRAINING
Visiting Associate. Diabetes Branch. NIDDK. National Institute of Health. Bethesda, Maryland, USA.
1986 | POSTDOCTORAL FELLOW
Division of Reproductive Endocrinology, OB/GYN. University of Maryland, Baltimore, Maryland. USA.
1978–79 | UNIVERSITY OF SALAMANCA
Anatomy classes at the Faculty of Medicine
1979 | CNS. Talavera de la Reina (Toledo)
Classes on Ovarian Physiology and Contraception
1982–86 | University of Maryland. USA
Theoretical and practical classes in Obstetrics and Gynaecology for students and residents
1991 | American Fertility and Sterility Meeting
Faculty of the American Fertility and Sterility Meeting, Montreal, Canadá.
1992 | Ramón Areces Foundation, Madrid
IV Post-Graduate International Course in Endocrinology
1995
XXIII SEGO Congress: “Molecular Biology Applied to Gynaecology” Sitges (Barcelona)

Serono Meetings in Human Reproduction: Update on the diagnosis of couples with reproductive dysfunction. El Escorial, Madrid

Director of the SEF-Campus: “Impact of Age on Reproduction”. Mérida, Cáceres

Organizer of the SEF-Campus: “Update on ART”. Salamanca

5th National Congress of the Spanish Association for the Study of Menopause: “Mechanism of Action of Steroids”. Valencia

1996 | Complutense University of Madrid
Complutense University of Madrid Summer Courses. “Oncogenes and Cancer”, Ronda, Málaga
1998
Serono Meetings in Human Reproduction: “Update on the diagnosis of couples with reproductive problems”

Serono Meetings in Human Reproduction: “Update on the diagnosis of couples with reproductive problems”. El Escorial, Madrid

Continuing Education Courses of the Medical Association of Cáceres: “Update on Infertility Issues”. Cáceres

Director of the Interactive Course on: “Inseminations and Semen Preparation”. FIV-Madrid Assisted Reproduction Clinic. Madrid

1999
Doctoral Course on Artificial Insemination and IVF. Cytoplasmic transfer. Hospital 12 de Octubre. Madrid

Doctoral Course on Intraovarian Regulation. Hospital de Santa Cruz y San Pablo, Barcelona, Spain

2000
Doctoral Course on Reproductive Physiology. Santiago de Compostela

Course on Assisted Reproduction. Topic: “Impact of ART on Obstetrics”. UIMP. Tenerife. Spain

SEF pre-congress course. Basic study of the infertile couple. Seville. Spain

2001
Intensive Continuing Education Course. “Virgen de las Nieves” University Hospital. Granada. Spain

Doctoral Course on Artificial Insemination. Hospital 12 de Octubre. Madrid

Doctoral Course on Menopause. Hospital Cruces. Bilbao. Spain

2002 | Hospital 12 de Octubre, Madrid
Doctoral Course on Artificial Insemination
2003
FIV-SKY, Instituto Dexeus. Baqueira-Beret, Cataluña, España.

Doctoral Course on Artificial Insemination and IVF. Santa Cristina University Hospital. UCM. Madrid

Current Topics in Infertility. University Hospital of Guadalajara. University of Alcalá de Henares

Doctoral Course on IVF. Hospital 12 de Octubre. UCM. Madrid

2004
Doctoral Course on Artificial Insemination and IVF. Santa Cristina University Hospital. UCM. Madrid

Doctoral Course on IVF. Hospital 12 de Octubre. UCM. Madrid

Doctoral Course on Menopause. Hospital Cruces. Bilbao. Madrid

Professor of the “Master’s Degree in Reproductive Medicine” (SEF/UCM). Madrid

2005
Doctoral Course on Artificial Insemination and IVF. Santa Cristina University Hospital. UCM. Madrid

Doctoral Course on IVF. Hospital 12 de Octubre. UCM. Madrid

Professor of the “Master’s Degree in Reproductive Medicine” (SEF/UCM). Madrid

2006-09
Doctoral Course on Artificial Insemination and IVF. Santa Cristina University Hospital. UCM. Madrid

Professor of the “Master’s Degree in Reproductive Medicine” (SEF/UCM). Madrid

Director of the Interactive Course on Artificial Insemination and IVF. FIVMadrid Clinic. Madrid

2010
Doctoral Course on Artificial Insemination and IVF. Santa Cristina University Hospital. UCM. Madrid

Professor of the “Master’s Degree in Reproductive Medicine” (SEF/UCM). Madrid

2011
Doctoral Course on Artificial Insemination and IVF. Santa Cristina University Hospital. UCM. Madrid

Doctoral Course on IVF. Hospital 12 de Octubre. UCM. Madrid

Professor of the “Master’s Degree in Reproductive Medicine” (SEF/UCM). Madrid

2011-2014
Doctoral Course on Artificial Insemination and IVF. Santa Cristina University Hospital. UCM. Madrid

Professor of the “Master’s Degree in Reproductive Medicine” (SEF/UCM). Madrid

1985
Cornelia P. Chaning Post-Doctoral Fellowship, Reproductive Research Foundation, University of Maryland School of Medicine, Baltimore, Maryland, USA.
2000
First prize for best scientific communication ASEBIR. Seville
2006
First prize for best basic communication. SEF. Zaragoza
2006
Second prize for best clinical communication. SEF. Zaragoza

1. De Pablo F, Miralles J, Hernández ER, García C, Corrales JJ, De Castro S: Study of the kinetics of thyroid hormones and the peripheral conversion rate of thyroxine to triiodothyronine in acute renal insufficiency under experimental conditions. Horm. Met. Res., 12: 529, 1980

2. Hernández ER: The fetus as a patient. JANO, 593: 34, 1982

3. De Pablo F, Roth J, Hernández ER, Pruss RM: Insulin is present in chicken eggs and early chick embryos. Endocrinology, 111: 1909, 1982

4. Taylor S, Dons RF, Hernández ER, Roth J, Gorden PH: Insulin resistance associated with androgen excess in women with autoantibodies to the insulin receptor. Ann. Inter. Med., 97: 851, 1982

5. De Pablo F, Hernández ER, Collia F, Gómez JA: Untoward effects of pharmacological doses of insulin in early chick embryos: through which receptor are they mediated? Diabetologia, 28: 308, 1985

6. De Pablo F, Girbau M, Gómez JA, Hernández ER, Roth J: Insulin antibodies retard and insulin accelerates growth and differentiation in early embryos. Diabetes, 34: 1063, 1985

7. De Pablo F, Lesniak M, Hernández ER, LeRoith D, Shiloach J, Roth J: Extracts of protozoa contain materials that react specifically in the immunoassay for guinea pig insulin. Horm. Met. Res., 18: 82, 1986

8. Hernández ER, Twardzik DR, Purchio A, Adashi EY: Gonadotropin-dependent ovarian transforming growth factor-β gene expression. Biol. Reprod., 36: 58A, 1987

9. Kudlow JE, Kobrin MS, Purchio AF, Twardzik DR, Hernández ER, Asa SL, Adashi EY: Ovarian transforming growth factor-β gene expression: immunohistochemical localisation to the theca-interstitial cells. Endocrinology, 121: 1577, 1987

10. Hernández ER, Resnick CE, Holtzclaw WD, Payne DW, Adashi EY: Insulin as a regulator of androgen biosynthesis by cultured rat ovarian cells: cellular mechanisms underlying physiological and pharmacological hormonal action. Endocrinology, 122: 2034, 1988

11. Hernández ER, Resnick CE, Svoboda ME, Van Wyk JJ, Payne DW, Adashi EY: Somatomedin-C/insulin-like growth factor-I (Sm-C/IGF-I) as an enhancer of androgen biosynthesis in cultured rat ovarian cells. Endocrinology, 122: 1603, 1988

12. Adashi EY, Resnick CE, Hernández ER, Svoboda ME, Van Wyk JJ: Characterisation and regulation of a specific cell membrane receptor for somatomedin-C/insulin-like growth factor-I in cultured rat granulosa cells. Endocrinology, 122: 194, 1988

13. Adashi EY, Resnick CE, Hernández ER, May JV, Knecht M, Svoboda ME, Van Wyk JJ: Somatomedin-C/insulin-like growth factor I as an amplifier of follicle-stimulating hormone action: studies on mechanisms and sites of action in cultured rat granulosa cells. Endocrinology, 122: 1583, 1988

14. Hernández ER, Jiménez JL, Payne DW, Adashi EY: Adrenergic regulation of ovarian androgen biosynthesis is mediated via β2-adrenergic theca-interstitial cell recognition sites. Endocrinology, 122: 1592, 1988

15. Adashi EY, Resnick CE, Hernández ER, Svoboda ME, Hoyt E, Clemmons D, Lund PK and Van Wyk JJ: Insulin-like growth factor I: a paradigm for putative intraovarian regulators. In: Hodgen, G.D., Rosenwaks, Z., Spieler, J.M. (eds.), Non-steroidal Gonadal Factors: Physiological Roles and Possibilities in Contraceptive Development. The Jones Institute Press, Norfolk, Virginia, p. 314, 1988

16. Adashi EY, Resnick CE, Hernández ER, Svoboda ME, Van Wyk JJ: In vivo regulation of granulosa cell somatomedin-C/insulin-like growth factor-I receptors. Endocrinology, 122: 1383, 1988

17. Adashi EY, Hernández ER, Resnick CE, Purchio AF, Twardzik DR, May JV: Ovarian transforming growth factor-β (TGF-β): sites and mechanisms of action. Mol. Cell. Endocrinol., 61: 247, 1989

18. Adashi EY, Resnick CE, Hernández ER, Svoboda ME, Hoyt E, Clemmons D, Lund PK, Van Wyk JJ: Rodent studies on the potential relevance of IGF-I to ovarian function. In: Hirshfield, A.N. (ed.), Growth Factors and the Ovary. Plenum Press, New York, p. 95-107, 1989

19. Adashi EY, Resnick CE, Hernández ER, Svoboda ME, Van Wyk JJ: The potential relevance of insulin-like growth factor I to ovarian physiology: from basic science to clinical application. Semin. Reprod. Endocrinol., 7: 94, 1989

20. Hernández ER, Roberts CT Jr., LeRoith D, Adashi EY: Rat ovarian insulin-like growth factor I (IGF-I) gene expression is granulosa cell-selective: 5’UT mRNA variant representation and hormonal regulation. Endocrinology, 125: 572, 1989

21. Hurwitz A, Hernández ER, Resnick CE, Packman JN, Payne D, Adashi EY: Basic fibroblast growth factor (B-FGF) inhibits gonadotropin-supported ovarian androgen biosynthesis: Mechanism(s) and site(s) of action. Endocrinology, 126: 3089, 1990.

22. Adashi EY, Resnick CE, Hernández ER, Hurwitz A, Rosenfeld RG: Follicle-stimulating hormone inhibits the constitutive release of insulin-like growth factor binding proteins by cultured rat ovarian granulosa cells. Endocrinology, 126: 1305, 1990.

23. Hernández ER, Purchio AF, Dhamarajan AM, Payne DW, Hurwitz A, Adashi, EY: Transforming growth factor-β (TGF-β) inhibits ovarian androgen production: Gene expression, cellular localisation, mechanism(s), and site(s) of action. Endocrinology, 127: 2804, 1990.

24. Hernández ER, Roberts CT,Jr., Hurwitz A, LeRoith D, Adashi EY: Rat ovarian insulin-like growth factor II gene expression is theca-interstitial cell-exclusive: Hormonal regulation and receptor distribution. Endocrinology, 127: 3249, 1990.

25. Adashi EY, Resnick CE, Hernández ER, Svoboda ME, Van Wyk JJ: Ovarian insulin-like growth factor I: Basic concepts leading to potential clinical outlets. In: LeRoith, D., Raizada, M.K. (eds.). Plenum Publishing Corp., New York, p. 141-151, 1989.

26. Adashi EY, Resnick CE, Hernández ER, Hurwitz A, Roberts CT,Jr., LeRoith D, Rosenfeld RG, Svoboda ME, Van Wyk JJ: The ovarian IGF-1 system as a paradigm for putative intraovarian regulators. In: Cittadini E, DeCecco L, Massi GB (Eds), Fertilita e Sterilita, Cosesa Edizioni, 1991,Volume 1, pp 209-213.

27. Adashi EY, Resnick, CE, Hurwitz A, Ricciarelli A, Hernández ER, Rosenfeld RG, Roberts CT,Jr., LeRoith D: The potential relevance of IGFs to ovarian physiology: Recent developments. Contraception. Fertilite’Sexualite, 19, pp 29-34, 1991.

28. Adashi EY, Resnick CE, Hernández ER, Hurwitz A, Roberts CT,Jr., LeRoith D, Rosenfeld RG, Svoboda ME, Van Wyk JJ: The ovarian IGF-I system as a paradigm for putative intraovarian regulators: In: Yen, S.S.C.and Vale, W.W. (eds.), Advances in Neuroendocrine Regulation of Reproduction: Basic and Clinical Aspects. Plenum Press, New York, 1990.

29. Adashi EY, Resnick CE, Hernández ER, Hurwitz A, Roberts CT,Jr., LeRoith D, Rosenfeld RG: The intraovarian Insulin-Like Growth Factor-I System. In: Schomberg, D.W. (ed.), Growth Factors in Reproduction. Plenum Press, New York, 1990. (pp 91).

30. Adashi EY, Resnick CE, Hernández ER, Svoboda ME, Hoyt E, Clemmons DR, Lund PK, Van Wyk JJ: Ovarian insulin-like factor-I: Basic and clinical implications. In: Haseltime, F.P. and Findlay, J. (eds.), Growth Factors in Fertility Regulations, 1990. (pp 117).

31. Adashi EY, Resnick CE, Hernández ER, Hurwitz A, Roberts CT,Jr., LeRoith D, Rosenfeld RG: The intraovarian IGF System. In: Dunaif, A., Givens, J.R., Haseltime, F.P. and Merriam, G.R. (eds.), The Polycystic Ovary Syndrome. Blackwell Scientific Publications, Inc., 1990. (pp 213).

32. Adashi EY, Resnick CE, Hernández ER, Hurwitz A, Rosenfeld, RG: Ovarian granulosa cell-derived insulin-like growth factor (IGF) binding proteins: Constitutive release of low molecular weight, high-affinity IGF-selective species. Mol. Cell. Endocrinol., 74: 175, 1990.

33. Adashi EY, Resnick CE, Hurwitz A, Ricciarelli E, Hernández ER, Rosenfeld RG: Ovarian granulosa cell-derived insulin-like growth factor binding proteins: Modulatory role of follicle-stimulating hormone. Endocrinology, 128: 754, 1990.

34. Adashi EY, Resnick CE, Hernández ER, Hurwitz A, Roberts CT,Jr., LeRoith D, Van Wyk JJ, Rosenfeld RG: Insulin-like growth factor-I as an intraovarian regulator: Basic and clinical implications. In: Seppala, M.and Hamberger L, (eds.), Frontiers in Human Reproduction. Ann. New York Acad. Sci., 626: 161, 1991.

35. Hernández ER, Roberts CT,Jr., Hurwitz A, Ricciarelli E, LeRoith D, Adashi EY: Rat ovarian insulin-like growth factor-I and II gene expression: Hormonal regulation and cellular localisation. In: Proceedings of the Second Sapparo International Symposium on Ovarian Function, T. Tanaka (ed.). Raven Press, 1991.

36. Hurwitz A, Hernández ER, Resnick CE, Packman JN, Payne DW, Adashi EY: Cytokine mediated regulation of ovarian function: Interleukin-I inhibits gonadotropin-induced androgen biosynthesis. Endocrinology, 129: 1250, 1991.

37. Adashi EY, Resnick C, Hernández ER, Hurwitz A, Roberts CT, LeRoith D, Rosenfeld RG. The intraovarian IGF system. ln: Shomber DW (ed). Growth Factors in Reproduction, Springer-Verlag, NY, pp 91, 1991.

38. Adashi EY, Resnick CE, Vera A, Hernández ER: In vivo regulation granulosa cell type I insulin-like growth factor receptors: Evidence for an inhibitory role for the putative endogenous ligand(s) of the ovarian GnRh receptors. Endocrinology, 128: 3130, 1991.

39. Adashi EY, Resnick CE, Hurwitz A, Hernández ER,: The ovarian IGF-I System. In: Spencer, EM (ed.), Modern Concepts of Insulin-like Growth Factors. Elsevier Science Publising Co., N.Y., 1991. (pp 267).

40. Adashi EY, Resnick CE, Hernández ER, Hurwitz A, LeRoith D, Roberts CT,Jr., Rosenfeld R, Svoboda ME, Van Wykk JJ: Growth factors and follicle function. In: Adashi EY, Mancuso S, Caruso A, Fulghern AM, Lanzone A (eds.) pg 111, 1991.

41. Ricciarelli E, Hernández ER, Hurwitz A, Kokia E & Rosenfeld RG, Schwander J, Adashi EY: The ovarian expression of the antigonadotropic IGFBP-2 is theca-interstitial cell-selective: Evidence for hormonal regulation. Endocrinology, 129: 2266, 1991.

42. Hernández ER, Hurwitz A, Botero L, Ricciarelli E, Werner H, Roberts CT,Jr., LeRoith D, Adashi EY: The insulin-like growth factor receptor gene family in the rat ovary: Divergent regulation of distinct receptor species. Mol. Endocrinol., 5: 1799, 1991.

43. Adashi EY, Resnick CE, Hurwitz A, Ricciarelli E, Hernández ER, Roberts CT,Jr., LeRoith D, Rosenfeld RG: Insulin-like growth factors: The ovarian connection. Human. Reprod., 6: 1206, 1991.

44. Hurwitz A, Ricciarelli E, Botero L, Rohan RM, Hernández ER, Adashi EY: Endocrine-mediated and autocrine-mediated regulation of rat ovarian (theca-interstitial) interleukin I beta gene expression. Gonadotropin-dependent preovulatory acquisition. Endocrinology, 129: 3427, 1991.

45. Adashi EY, Resnick CE, Hurwitz A, Ricciarelli E, Hernández ER, Rosenfeld RG: Ovarian granulosa cell-derived insulin-like growth factor binding proteins: Modulatory role of follicle-stimulating hormone. Endocrinology, 128: 745, 1991.

46. Adashi EY, Resnick C, Ricciarelli E, Hurwith A, Kokia E, Botero LF, Tedeschi C, Hernández ER, Koistinen R, Rutanen EM, Seppala M. Local tissue modification of follicle-stimulating hormone action. In: Genazzani AR, Petraglia F (eds). Hormones in Gynaecological Endocrinology. The Parthenon Publishing Group, Lancs, England, pp 255, 1992.

47. Adashi EY, Resnick CE, Ricciarelli E, Hurwitz A, Hernández ER, Rosenfeld RG, Ballard FJ, Carlson-Skwirut C: Granulosa cell-derived insulin-like growth factor (IGF) binding proteins are inhibitory to IGF-I hormonal action: Evidence derived from the use of a truncated IGF-I analogue. J. Clin. Invest., 90: 1593, 1992.

48. Hurwitz A, Loukides J, Ricciarelli E, Botero L, Katz E, Mc Allister JM,Garcia J, Rohan RM, Adashi EY, Hernández ER: The human intraovarian Interleukin-1 (IL-1) system: highly-compartmentalised and hormonally- dependent regulation of the genes encoding IL-1, its receptor, and its receptor antagonist. J. Clin. Invest., 89: 1746, 1992.

49. Ricciarelli E, Hernández ER, Tedeschi C, Botero L, Kokia E, Rohan RG, Rosenfeld RG, Albiston AL, Herington AC, Adashi EY: Rat ovarian insulin-like growth factor binding protein-3-A Growth Hormone-Dependent Theca- Interstitial Cell-derived Antigonadotropin. Endocrinology, 130: 3092, 1992.

50. Adashi EY, Resnick CE, Ricciarelli E, Hurwitz A, Kokia E, Botero L, Tedesache C, Hernández ER, Koistinen R, Rutanen EM, Seppala M.Local tissue modification of FSH hormone action. In: Genazzani AR, Petraglia F (eds), Hormones in Gynecological Endocrinology. The Parthenon Publishing Group, Lancs, England, pp 255, 1992.

51. Hernández ER, Roberts CT,Jr., Hurwitz A, Ricciarelli E, LeRoith D, Adashi EY: Rat ovarian IGF-I and II gene expression: Hormonal regulation and cellular localisation. In: Fujimoto S, Mizuno M and Gegal Sj (Ed), Serono Symposia Review No 28, Recent Advances in Ovarian Function: Basic and Clinical Researches, pp 113, 1992.

52. Hernández ER, Hurwitz A, Pellicer A, Adashi EY, LeRoith D, Roberts CT,Jr: Expression of the insulin-like growth factor and insulin-like growth factor receptor gene families in the human ovary. J. Clin. Endo. Metab. 74: 419, 1992.

53. Adashi EY, Resnick C, Hernández ER, Hurwith A, Roberts CT, LeRoith D, Rosenfeld RG. The intraovarian IGF system. In Dunaif A, Givens JR, Haseltine FP, Merrian GR. (eds) Polycystic Ovarian Syndrome, Blackwell Scientific Publications Inc., pp 213, 1992.

54. Adashi EY, Resnick C, Hurwitz A, Kokia E, Ricciarelli E, Roberts CT, LeRoith D, Rosenfeld RG. The ovarian and testicular IGF system. In: Nieschlag E and Habenicht F, Molecular, cellular and endocrine events in male reproduction: Spermatogenesis, Fertilization, Contraception. Schering Foundation Workshop 4, Springer-Verlag, Berlin, pp 113, 1992.

55. Levy MJ, Hernández ER, Adashi EY, Stillman RJ, Roberts CT,Jr. and LeRoith D: Expression of IGF-I, IGF-II and the IGF-l and IGFII receptor genes during postnatal development of the rat ovary. Endocrinology, 131: 1202, 1992.

56. Phillip M, Palese T, Kowarski AH, Hernández ER, Roberts CT,Jr. and LeRoith D: Testosterone has no direct effect on hepatic IGF-I gene expression. Endocrinology, 130: 2865, 1992.

57. Adashi EY, Resnick CE, Hurwitz A, Ricciarelli E, Hernández ER, Roberts CT,Jr, LeRoith D, Rosenfeld R G. The intraovarian IGF System. Growth. Reg., 2: 10, 1992.

58. Adashi EY, Resnick CE, Hurwitz A, Kokia E, Ricciarelli E, Hernández ER, Roberts CT,Jr., LeRoith D, Rosenfeld RG. Ovarian Growth Factors: The IGF-I example. In Nieschlag E. (ed). Molecular and cellular endocrine events in male reproduction. Springer-Verlag, Berlin., pp.143, 1992.

59. Hurwitz A, Hernández ER, Payne D, Dharmarajan AM, Adashi EY.Interleukin-1 is both morphogenic and cytotoxic to cultured rat ovarian cells. Obligatory role for heterologous, contact-independent cell-cell interaction. Endocrinology, 131: 1643, 1992.

60. Botero L, Kokia E, Ricciarelli E, Roberts CT, LeRoith D, Adashi EY, Hernández ER: IGF-I gene and type I IGF gene expression by primary cultures of ovarian cells: Insulin and dexamethasone-dependence. Endocrinology, 132: 2703, 1993.

61. Adashi EY, Resnick CE, Hernández ER, LeRoith D, Robert CT,Jr and Rosenfeld RG: Intraovarian Regulators: The proposed role of IGFs. In: Chrousos GP (ed), Intraovarian regulators and Polycystic Ovarian Syndrome: Recent Progress in Clinical and Therapeutic Aspects, Ann. New York Acad. Sci., 1993.

62. Adashi EY, Resnick CE, Hurwitz A, Ricciarelli E, Hernández ER, Botero L, Roberts CT,Jr, LeRoith D, Rosenfeld RG: The intraovarian IGF System as a Paradigm for Intraovarian Regulators. In: Magness RR, Naftolin F. (Eds), Local Systems in Reproduction, 1993.

63. Hernández ER. IGF-I intraovarico, Boletin de la Sociedad Española de Fertilidad (SEF), 3:20, 1994

64. Hernandez ER. PCR en Reproducción. Boletin de la SEF, 4:10, 1995

65. Hernández ER, Ricciarelli E: Existe alguna relación entre el Premio Nobel y la temperatura de los testículos? Endocrinologia, 42: 35-36, 1995.66. Hernández ER. Regulation of the IGFs and their receptor genes by steroids and gonadotropins in the ovary. J. Steroid. Biochem. Molec. Biol,: 219-221, 1995.

67. Flyvberg A, Landau D, Domene H, Hernández ER, LeRoith D. The role of GH, IGF-Is and IGFBPs in experimental diabetic kidney disease. Metabolism, 44: 670-71, 1995.

68. Goya L, Rivero F, Martin MA, Hernández ER, Pascual-Leone AM. Effects of reefeding of undernourished and insulin treatment of diabetic neonatal rats on serum and liver mRNA expression of IGFs and IGFBPs. Am. J. Physical., 271: E223-E231, 1996.

69. Hernández ER, Ricciarelli E. Desarrollo folicular: Factores de Crecimiento. pg 50-62. Remohi J, Pellicer A (eds) 1996.

70. Hernández ER. Endocrinologia de la reproducción. En «Fundamentos Moleculares del Sistema Endocrino». Blazquez E (ed). 1996.

71. Porras A, Hernández ER, Benito M. Ras proteins mediate induction of uncoupling protein, IGF-I and IGF-I receptor in rat fetal brown adipocytes cell lines. DNA and Cell. Biol., 15: 921. 1996.

72. Hernández ER Apoptosis en Reproducción Humana. Boletin de SEF 6:10-14, 1997

73. Alcaide A, Hernández, ER. Infertilidad de origen masculino: tratamientos actuales. Endocrinología, 44:155-157, 1997.

74. Hernández ER. ICSI y Consejo Genético. Boletín de la SEF. 7: 223-24, 1998

75. Roldán ERS, Hernández ER. Descenso en la calidad del semen humano: contaminantes ambientales y microdelecciones del cromosoma Y. Endocrinología, 45: 298-302, 1998.

76. Hernández, ER. The clinical benefits of recombinant gonadotropins: The good, the bad and the ugly. Hum. Reprod.14:1417-1418, 1999.

77. Peramo B, Ricciarelli E, Hernández ER. Transferencia de embriones: La gran olvidada. Boletin de la SEF 8: 18-24, 1999

78. Hernández ER, Garcia-Bermudez M, Roldan E, Ricciareli E. Estudio previo a la reproducción asistida. Revista Iberoamericana de Fertilidad 4:19-22, 1999

79. Hernández ER. Todas las FSH son iguales ante los ojos del receptor. Boletín de la SEF 8: 32-33,1999

80. Cuadros J, Hernández ER. Clonación: Historia, técnica y utilidad. Revista Ibero-Americana de fertilidad 16: 65-68, 1999.

81. Peramo B, Ricciarelli E, Hernández ER. Blastocyst Transfer and Monocygotic Twinning. Fertil. Steril, 11:16-23, 1999.

82. Cuadros J, Hernández ER. Aspectos éticos de la clonación. Boletín de la SEF 7: 15-18, 1999

83. Hernández ER. Aplicación clínica de la FSH recombinante. En Avances en Menopausia y Reproducción. Vázquez (ed), Pag.136, 1999

84. Peramo B, Ricciarelli E, Hernández ER. Factores que influyen en los fallos de Fecundación In Vitro. Boletín de la SEF 8: 7-16, 1999

85. Peramo B, Ricciarelli E, Hernández ER. Mecanismo de Acción de las hormonas esteroides. En “Moduladores selectivos de los receptores de estrógenos (SERM): Aspectos básicos y clínicos”. A. Cano y J. Calaf (eds.), Doyma SA, Barcelona, pp 15-22, 1999

86. Cuadros J, Hernández ER. Transferencia citoplasmática. Boletín de ASEBIR 2:43-45, 1999

87. Hernandez ER. The clinical benefits of recombinant gonadotropins. Human Reproduction 15: 734-735, 2000

88. Hernandez ER. Embryo implantation: The rubicon for GnRH antagonist Human Reprod 15:1211-1216, 2000

89. Peñarrubia J, Balasch J, Garcia-Bermudez M, Casamitjana R, Vanrell JA, Hernández ER. Growth Hormone does not increase the expression of IGF-I and their receptor genes in the premenopausal human ovary. Human Reprod 15:1241-1246, 2000

90. Peramo B, Ricciareli E, Hernandez ER. Gestacion con agonistas de la GnRH. Progresos en Obstetricia y Ginecología. 43:521-526, 2000

91. Hernández ER. No room on the carrousel for meeting of like minds. Nature 407: 285, 2000

92. Hernández ER. Avoiding multiple pregnancies: sailing uncharted seas. Human Reproduction 16: 615-616, 2001

93. Hernández ER. El principio del fin de la donación de ovocitos. Rev Ibero Americana de Infert 18: 201-202, 2001

94. Hernández ER. La clonación. Progresos en Obstetricia y Ginecología. 44:281-282, 2001

95. Hernández ER. La clonación terapéutica. Rev IberoAmericana de Infert 18: 201-202, 2001

96. Roncero C, Hernandez ER. Introduccion a la biologia molecular. En: Biologia
Molecular en Medicina Reproductiva (Hernandez ER, Horcajadas JA, Simon C. Eds) Vol. 8 (2): 17-30, 2002. Panamericana, Madrid, España

97. Martinez M, Cuadros J, Andres L, Ricciarelli E, Hernandez ER. Técnicas en biologia molecular. En: Biologia Molecular en Medicina Reproductiva (Hernandez ER, Horcajadas JA, Simon C., Eds) Vol. 8 (2): 31-48, 2002.
Panamericana, Madrid, España

98. Cuadros J, Andres L, Martinez M, Ricciarelli E, Hernandez ER. Clonacion. En: Biologia Molecular en Medicina Reproductiva (Hernandez ER, Horcajadas JA, Simon C., Eds) Vol. 8 (2): 199-208, 2002. Panamericana, Madrid, España

99. Acevedo B, Gómez JL, Ricciarelli E, Hernández ER. Efectos secundarios de la punción transvaginal. Revista IberoAmericana de Infertilidad 20:31-34, 2003

100. Ricciarelli E, Sánchez-Burgos M, Sánchez M, Cuadros J, Hernández ER. Impact of the antagonist of GnRH in oocyte donation. Fertil Sterilility 79:1461-1463; 2003

101. Acevedo B, Gómez JL, Hernández ER Ricciarelli E. LH-supplementation increase pregnancy rates in GnRH antagonist donor cycles. Fertil Sterilility 82:343-347, 2004

102. Gómez JL Acevedo B, Ricciarelli E, Hernández ER. Timing ovulation for intrauterine insemination with a GnRH antagonist. Human Reproduction 20:368-372, 2005.

103. Gómez JL Acevedo B, Ricciarelli E, Hernández ER. LH improves early follicular recruitment in women over 38 years old. RBMOnline 11:409-414, 2005

104. Gómez JL Acevedo B, Ricciarelli E, Hernández ER. Requerimientos de la LH en estimulación ovárica: la ventana terapéutica. CMR 11:45-53, 2005

105. M Sánchez, J Cuadros, L Andrés, E Ricciarelli, ER Hernández. Diagnostico Genético Preimplantacional para enfermeras. Libro de “Reproducción Asistida para Enfermeras”. Publicado por la SEF.

106. Sanchez Aparicio P, Martinez M, Cuadros J, Ricciarelli E, Heranandez ER. Estudio de la expresion del gen de la insulina y su receptor en ovocitos y embriones humanos. Rev Iberoam Ferilidad 23: 387-394, 2006

107. Acebedo B, Gomez-Palomares JL, Ricciarelli E, Hernández, ER. Triggering ovulation with GnRH agonists does not compromise embryo implantability. Fertil Sterility 86:1682-87, 2006

108. Gomez-Palomares JL, Hernández, ER, Ricciarelli E. Multifollicular recruitment in combination with Gonadotropin-releasing hormone antagonist increased pregnancy rates in intrauterine insemination cycles. Fertil Steril. 2008, 89: 620-4.

109. Hernández, ER, Gomez-Palomares JL, Ricciarelli E. No room for cancellation, coasting, or ovarian hyperstimulation syndrome in oocyte donation cycles. Fertil Steril. 2009, 9: 1358-61.

110. Hernández ER. What next for preimplantation genetic screening (PGS)? Beyond Aneuploidy. Hum Reprod. 2009, 24:1538-41

111. Manzanares MA, Gómez-Palomares JL, Ricciarelli E, Hernández ER. Triggering ovulation with gonadotropin-releasing hormone agonist in vitro fertilization patients with polycystic ovaries does not cause ovarian hyperstimulation syndrome despite very high estradiol levels. Fertil Steril. 2010, 93:1215-9.

112. Hernandez ER, Nieto M, Gomez-Palomares JL. Fecundación e Implantación Embrionaria. En: Fundamentos de Reproducción (Arenas JM y Coroleu B, eds), SEGO y SEF, Madrid, 2010, pag. 36-40

113. Hernandez ER. Disfunción Reproductiva: una definición global de la infertilidad para el siglo 21. Rev Iberoam Fertilidad 28: 199-200, 2011

114. Manzanares MA, Ricciarelli E, Hernández ER. Ventajas de la maduración ovocitaria con análogos de la GnRH en TRA. Rev Iberoam Fertilidad 29: 129-135, 2012

115. Hernández ER. Desafíos médicos y legales en el futuro de la reproducción humana. En Reproducción Humana Asistida: Aspectos Jurídicos, Sociales y Psicológicos. 2013. Giuliana Baccino (ed.). Editorial Tirant Lo Blanch. Madrid

116. Baccino G, Salvadores P, Hernández ER. Disclosing their type of conception to offspring conceived by gamete or embryo donation in Spain. J Reproduction and Infant Psychol, 2013

Dra. Elisabetta Ricciarelli

FOUNDER OF FIVMADRID | Bachelor of Medicine and Surgery
University studies
Bachelor’s Degree in Medicine and Surgery. Cum Laude. University of Bologna, Italy
INTERNSHIP AND RESIDENCY
Residency in Obstetrics and Gynaecology. Cum Laude. University Hospital of Parma, Italy
1996 - CERES Congress Madrid
Assisted reproduction techniques
1997 - Continuing Education Courses of the Cáceres Medical Association
Women's Day Conference, "The Aging Woman"
1997 - Serono Meeting on Human Reproduction in EL ESCORIAL (MADRID)
"Artificial insemination and IVF, coordination between gynecologists and assisted reproduction centers"
1997/1998 - FIVMadrid Assisted Reproduction Clinic
Interactive Courses on: "Inseminations and Semen Preparation".
2000 - Madrid Medical Association – APROIN Conference
"Current Trends in Assisted Reproduction Techniques"
2001 - Madrid Medical Association – APROIN Conferences
"Egg Donation." / "Polycystic Ovaries." / "The Male Factor in Assisted Reproduction."
2001 - FIVMADRID CLINIC
Training courses for paramedical staff
2007 - Serono Symposia International in Madrid
VF preceptorship-ART: "Current practice in the XXI century"
1993 - ISDIN AWARD
Title of the study: Does the use of growth hormone in in vitro fertilisation cycles make sense? Study on the expression of the growth hormone receptor gene in the human ovary. Monograph available

1. Ricciarelli E, Hernandez ER, Hurwizt A, Kokia E, Rosenfeld RG, Schwander J and Adashi EY: The ovarian expression of the antigonadotropic IGFBP-2 is theca-interstitial cell-selective: Evidence for hormonal regulation. Endocrinology 129: 2266, 1991.

2. Adashi EY, Resnick, CE, Hurwitz A, Ricciarelli E, Hernandez ER, Rosenfeld RG, Roberts CT Jr., LeRoith D: The potential relevance of IGFs to ovarian physiology: Recent developments. Contraception. Fertilité Sexualité, 1991, Volume 19, pp 29-34.

3. Adashi EY, Resnick CE, Hurwtiz A, Ricciarelli E, Hernandez ER, Rosenfeld RG: Ovarian granullosa cell-derived insulin-like growth factor binding proteins: Modulatory role of follicle-stimulating hormone. Endocrinology 128: 754, 1990.

4. Hernandez ER, Roberts CT, Jr., Hurwitz A, Ricciarelli E, LeRoith D, Adashi EY: Rat ovarian insulin-like growth factor-I and II gene expression: Hormonal regulation and cellular localization. In: Proceedings of the Second Sapparo International Symposium on Ovarian Function, T.Tanaka (ed.). Raven Press, 1991.

5. Hernandez ER, Hurwitz A, Botero L, Ricciarelli E, Werner H, Roberts CT, Jr., LeRoith D, Adashi EY: The insulin-like growth factor receptor gene family in the rat ovary: Divergent regulation of distinct receptor species. Mol Endocrinol 5: 1799, 1991.

6. Adashi EY, Resnick CE, Hurwitz A, Ricciarelli E, Hernandez ER, Roberts CT, Jr., LeRoith D, Rosenfeld RG: Insulin-like growth factors: The ovarian connection. Human Reprod. 6: 1206, 1991.

7. Hurwitz A, Ricciarelli E, Botero L, Rohan RM, Hernandez ER, Adashi EY: Endocrine-mediated and autocrine- mediated regulation of rat ovarian theca- interstitial interlukin-1 gene expression. Gonadotropin-dependent preovulatory acquisition. Endocrinology 129: 3427, 1991.

8. Adashi EY, Resnick CE, Hurwitz A, Ricciarelli E, Hernandez ER, Rosenfeld RG: Ovarian granullosa cell-derived insulin-like growth factor binding proteins: Modulatory role of follicle-stimulating hormone. Endocrinology 128: 745, 1991.

9. Adashi EY, Resnick C, Ricciarelli E, Hurwith A, Kokia E, Botero LF, Tedeschi C, Hernandez ER, Koistinen R, Rutanen EM, Seppala M. Local tissue modification of follicle-stimulating hormone action. In: Genazzani AR, Petraglia F (eds). Hormones in gynecological endocrinology. The Parthenon Publishing Group, Lancs, Englan, pp 255, 1992.

10. Adashi EY, Resnick CE, Ricciarelli E, Hurwitz A, Hernandez ER, Rosenfeld RG, Ballard FJ, Carlson-Skwirut C: Granullosa cell-derived insulin-like growth factor (IGF) binding proteins are inhibitory to IGF-I hormonal action: Evidence derived from the use of a truncated IGF-I analog. J Clin Invest 90: 1593, 1992.

11. Hurwtiz A, Loukides J, Ricciarelli E, Botero L, Katz E, Mc Allister JM, Garcia J, Rohan RM, Adashi EY and Hernandez ER: The human intraovarian Interlukin -1 (IL-1) system: highly-compartmentalized and hormonally- dependent regulation of the genes encoding IL-I, its receptor, and its receptor antagonist. J Clin Invest 89: 1746, 1992.

12. Ricciarelli E, Hernandez ER, Tedeschi C, Botero L, Kokia E, Rohan RG, Rosenfeld RG, Albiston AL, Herington AC, Adashi EY: Rat ovarian insulin-like growth factor binding protein-3: A Growth Hormone-Dependent Theca- Interstitial Cell-derived Antigonadotropin. Endocrinology 130:3092, 1992.

13. Adashi EY, Resnick CE, Ricciarelli E, Hurwitz A, Kokia E, Botero L, Tedeschi C, Hernandez ER, Koistinen R, Rutanen EM and Seppala M. Local tissue modification of FSH hormone action, In: Genazzani AR and Petraglia F (eds), Hormones in Gynecological Endocrinology. The Parthenon Publishing Group, Lancs, England, pp 255, 1992.

14. Hernandez ER, Robet CT, Hurwitz A, Ricciarelli E, LeRoith D and Adashi EY: Rat ovarian IGF-I and II gene expression: Hormonal regulation and cellular localization. In: Fujimoto S, Mizuno M and Gegal Sj (Ed), Serono Symposia Rewiev No 28, Recent advances in ovarian function: Basic and clinical researches, pp 113, 1992.

15. Adashi EY, Resnick C, Hurwith A, Kokia E, Ricciarelli E, Roberts CT, LeRoith D, Rosenfeld RG. The ovarian and testicular IGF system. In: Nieschlag E and Habenicht F, Molecular, cellular and endocrine events in male reproduction: Spermatogenesis, Fertilization, Contraception. Schering Foundation Workshop 4, Springer~Verlag, Berlin, pp 113, 1992.

16. Adashi EY, Resnick CE, Hurwitz A, Ricciarelli E, Hernandez ER, Roberts CT Jr, LeRoith D and Rosenfeld R G. The intraovarian IGF System. Growth Reg 2: 10, 1992.

17. Adashi EY, Resnick CE, Hurwitz A, Kokia E, Ricciarelli E, Hernandez ER, Roberts CT, LeRoith D, and Rosenfeld RG. Ovarian Growth Factors: The IGF-I example. In Nieschlag E. (ed). Molecular and cellular endocrine events in male reproduction. Spring- Verlag, Berlin., pp.143, 1992.

18. Botero L, Kokia E, Ricciarelli E, Roberts CT, LeRoith D, Adashi EY and Hernandez ER: IGF-I gene and type I IGF gene expression by primary cultures of ovarian cells: Insulin and dexamethasone-dependence. Endocrinology 132: 2703, 1993.

19. Adashi EY, Resnick CE, Hurwitz A, Ricciarelli E, Hernandez ER, Botero L, Roberts CT. Jr, LeRoith D, and Rosenfeld RG. The intraovarian IGF System as a Paradigm for intraovarian regulators. In: Magness RR and Naftolin F. (Eds), Local Systems in Reproduction, 1993.

20. Hernández ER, Ricciarelli E. ¿Existe alguna relacion entre el Premio Nobel y la temperatura de los testículos?. Endocrinologia 42: 35-36, 1995.

21. Hernández ER, Ricciarelli E. Desarrollo folicular: Factores de Crecimiento. pp 50-62. Remohi J, Pellicer A (eds). 1996.

22. Putoski L, Rohan R. Choi DS, Scherzer W, Ricciarelli E, Mordacq J, Mayo K, Adashi E. Rat ovarian insulin-like growth factor binding protein 4: a hormone dependent granullosa cell derived antigonadotropin. J. Soc. Gynecol. Invest Vol. 4, N 3, May/June 1997.

23. Peramo B, Ricciarelli E, Hernandez ER. Transferencia de embriones: La gran olvidada. Boletín de la SEF 8: 18-24, 1999.

24. Hernandez ER, Garcia-Bermudez M, Roldan E, Ricciarelli E. Estudio previo a la reproducción asistida. Revista Iberoamericana de Fertilidad 4: 19-22, 1999.

25. Peramo B, Ricciarelli E, Hernández ER. Blastocyst Transfer and Monocygotic Twinning. Fertil. Steril. 1999.

26. Peramo B, Ricciarelli E, Hernández ER. Mecanismo de Acción de las hormonas esteroides. En “Moduladores selectivos de los receptores de estrógenos (SERM): Aspectos básicos y clínicos”. A. Cano y J. Calaf (eds.), Doyma SA, Barcelona, pp 15-22, 1999.

27. Peramo B, Ricciarelli E, Hernandez ER. Gestación con agonistas de la GnRH. Progresos en Obstetricia y Ginecología. 43: 521-526, 2000.

28. Acevedo B, Gómez JL, Ricciarelli E, Hernández ER. Efectos secundarios de la punción transvaginal. Revista IberoAmericana de Infertilidad 20: 31-34, 2003.

29. Ricciarelli E, Sánchez-Burgos M, Sánchez M, Cuadros J, Hernández ER. Impact of the antagonist of GnRH in oocyte donation. Fertil Sterilility 79: 1461-1463; 2003.

30. Acevedo B, Gómez JL, Hernandez ER, Ricciarelli E. LH-supplementation increase pregnancy rates in GnRH antagonist donor cycles. Fertil Sterilility 82: 343-347, 2004.

31. Gómez JL Acevedo B, Ricciarelli E, Hernández ER. Timing ovulation for intrauterine insemination with a GnRH antagonist. Human Reproduction 20: 368-372, 2005.

32. Gómez JL Acevedo B, Ricciarelli E, Hernández ER. LH improves early follicular recruitment in women over 38 years old. RBMOnline 11: 409-414, 2005.

33. Gómez JL Acevedo B, Ricciarelli E, Hernández ER. Requerimientos de la LH en estimulación ovárica: la ventana terapéutica. CMR 11: 45-53, 2005.

34. M Sánchez, J Cuadros, L Andrés, E Ricciarelli, ER Hernández. Diagnostico Genético Preimplantacional para enfermeras. Libro de “Reproducción Asistida para Enfermeras”. Publicado por la SEF.

35. Sánchez Aparicio P, Martinez M, Cuadros J, Ricciarelli E, Hernández ER. Estudio de la expresión del gen de la insulina y su receptor en ovocitos y embriones humanos. Rev Iberoam Fertilidad 23: 387-394, 2006.

36. Acevedo B, Gómez-Palomares JL, Ricciarelli E, Hernández, ER. Triggering ovulation with GnRH agonists does not compromise embryo implantability. Fertil Sterility 86: 1682-87, 2006.

37. Gómez-Palomares JL, Acevedo-Martín B, Chávez M, Manzanares MªA, Ricciarelli E, Hernández ER. Multifollicular recruitment in combination with gonadotropin-releasing hormone antagonist increased pregnancy rates in intrauterine insemination cycles. Fertility Sterility vol. 89, no. 3: 620-624, 2008.

38. Hernández ER, Gómez-Palomares JL, Ricciarelli E. No room for Ovarian Hyperstimulation Síndrome (OHHS) in oocyte donor cycles. Fertil Sterility 2010

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